2017年考研数学(数二)模拟题
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相关推荐:>>>2017年全国硕士研究生报名指导专题>>>2017年考研报名时间、考研报名入口专题>>>全国各地2017年考研报考点汇总>
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相关推荐:>>>2017年全国硕士研究生报名指导专题>>>2017年考研报名时间、考研报名入口专题>>>全国各地2017年考研报考点汇总>
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At18,AshanthiDeSilvaofsuburbanClevelandisalivingsymbolofoneofthegreatintellectualachievementsofthe20thcentury.Bornwithanextremelyrareandusuallyfataldisorderthatleftherwithoutafunctioningimmunesystem(the“bubble-boydisease,”namedafteranearliervictimwhowaskeptaliveforyearsinasterileplastictent),shewastreatedbeginningin1990witharevolutionarynewtherapythatsoughttocorrectthedefectatitsverysource,inthegenesofherwhitebloodcells.Itworked.Althoughherlastgene-therapytreatmentwasin1992,sheiscompletelyhealthywithnormalimmunefunction,accordingtooneofthedoctorswhotreatedher,W.FrenchAndersonoftheUniversityofSouthernCalifornia.Researchershavelongdreamedoftreatingdiseasesfromhemophiliatocancerbyreplacingmutantgeneswithnormalones.Andthedreamingmaycontinuefordecadesmore.“Therewillbeagene-basedtreatmentforessentiallyeverydisease,”Andersonsays,“within50years.”It'snotentirelyclearwhymedicinehasbeensoslowtobuildonAnderson'searlysuccess.TheNationalInstitutesofHealthbudgetofficeestimatesitwillspend$432millionongene-therapyresearchin2005,andthereisnoshortageofpromisingleads.Thetherapeuticgenesareusuallydeliveredthroughvirusesthatdon'tcausehumandisease.“ThevirusissortoflikeaTrojanhorse,”saysRonaldCrystalofNewYorkPresbyterian/WeillCornellMedicalCollege.“Thecargoisthegene.”AttheUniversityofPennsylvania'sAbramsonCancerCenter,immunologistCarlJunerecentlytreatedHIVpatientswithageneintendedtohelptheircellsresisttheinfection.AtCornellUniversity,researchersarepursuinggene-basedtherapiesforParkinson'sdiseaseandararehereditarydisorderthatdestroyschildren'sbraincells.AtStanfordUniversityandtheChildren'sHospitalofPhiladelphia,researchersaretryingtofigureouthowtohelppatientswithhemophiliawhotodaymustinjectthemselveswithexpensiveclottingdrugsforlife.Animalexperimentshaveshowngreatpromise.Butsomehow,thingsgetlostinthetranslationfromlaboratorytopatient.Inhumantrialsofthehemophiliatreatment,patientsshowaresponseatfirst,butitfadesovertime.Andthefieldhasstillnotrecoveredfromthesetbackitsufferedin1999,whenJesseGelsinger,an18-year-oldwithararemetabolicdisorder,diedafterreceivinganexperimentalgenetherapyattheUniversityofPennsylvania.Someexpertsworrythatthefieldwillbetarnishedfurtherifthenextpeopletobenefitarenotpatientsbutathletesseekinganedge.Thissummer,researchersattheSalkInstituteinSanDiegosaidtheyhadcreateda“marathonmouse”byimplantingagenethatenhancesrunningability;already,officialsattheWorldAnti-DopingAgencyarepreparingtotestathletesforsignsof“genedoping.”Buttheprincipleisthesame,whetheryou'retryingtohelpahealthyrunnerrunfasterorallowamuscular-dystrophypatienttowalk.“Everybodyrecognizesthatgenetherapyisaverygoodidea,”saysCrystal.“Andeventuallyit'sgoingtowork.”1.ThecaseofAshanthiDesilvaismentionedinthetextto____________.[A]showthepromiseofgene-therapy[B]giveanexampleofmoderntreatmentforfataldiseases[C]introcetheachievementofAndersonandhisteam[D]explainhowgene-basedtreatmentworks2.Anderson‘searlysuccesshas________________.[A]greatlyspeededthedevelopmentofmedicine[B]broughtnoimmediateprogressintheresearchofgene-therapy[C]promisedacuretoeverydisease[D]madehimanationalhero3.Whichofthefollowingistrueaccordingtothetext?[A]Ashanthineedstoreceivegene-therapytreatmentconstantly.[B]Despitethehugefunding,generesearcheshaveshownfewpromises.[C]Therapeuticgenesarecarriedbyharmlessviruses.[D]Gene-dopingisencouragedbyworldagenciestohelpathletesgetbetterscores.4.Theword“tarnish”(line5,paragraph4)mostprobablymeans____________.[A]affect[B]warn[C]trouble[D]stain5.Fromthetextwecanseethattheauthorseems___________.[A]optimistic[B]pessimistic[C]troubled[D]uncertain答案:ABCDA
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