-
朱海亮,男,教授,博士生导师,。1965年3月出生于安徽省阜阳市。zhuhl@nju.e.cn;18913938847一、简历1988年兰州大学化学系获硕士学位;1988-1994年宁夏大学化学系讲师;1998年南京大学化学化工学院获博士学位;2000年中山大学化学与化学工程学院博士后,副研究员;2000-2001德国Philipps-UniversityMarburg化学系有机化学研究所二站博士后2002-2011年武汉科技学院环境学院,南京大学生命科学学院,教授;2011-,山东理工大学生命科学学院,南京大学生命科学学院,教授。二、专业及方向:化学生物学、药物合成化学三、主持的基金项目主持973子课题、863子课题、国家支撑计划子课题、国家重大科技专项(河流主题)子课题、中央高校基本科研业务费专项资金创新团队、国家科技型中小企业技术创新基金、国家自然科学基金、湖北省创新团队、湖北省杰出青年基金等基金项目多项。指导的博士后在站期间获得中国博士后基金项目12项。四、奖励和荣誉(1)朱海亮、李环球、石磊、肖竹平、程魁、黄险峰、李玉广、由忠录、史大华,"市场药物及天然活性物质的结构改造、结构分析及其生物活性研究",2008年度,教育部自然科学二等奖。(2)朱海亮、陈悟、李玉广、由忠录,"天然活性物质的结构改造及其药物活性研究",2009年度,湖北省自然科学三等奖。(3)2009-,任Curr.Med.Chem.杂志Anti-CancerAgentsinMedicinalChemistry专栏副主编。(4)2008入选中国科学院"百人计划"学者。(5)2008-2011全国百篇优秀博士论文评审专家。(6)2003湖北省"有突出贡献的中青年专家"。五、发表SCI收录论文400余篇,论文被SCI刊物引用2000余次。发表的部分论文目录如下(带星号*的为通讯作者)。1.XiangLu,HuiZhang,XiLi,GuoChen,Qing-ShanLi,YinLuo,Ban-FengRuan,Xian-WeiChen,Hai-LiangZhu*,Design,synthesisandbiologicalevaluationofpyridineacylsulfonamidederivativesasnovelCOX-2inhibitors,Bioorg.Med.Chem.,2011,19,6827-6832.2.KaiLiu,Hai-LiangZhu*,NitroimidazolesasAnti-TumorAgents,Anti-CancerAgentMed.Chem.,2011,11,687-691.3.Xiao-MinZhang,MinQiu,JuanSun,Yan-BinZhang,Yu-ShunYang,Xiao-LiangWang,Jian-FengTang,Hai-LiangZhu*,Synthesis,biologicalevaluation,andmoleculardockingstudiesof1,3,4-oxadiazolederivativespossessing1,4-benzodioxanmoietyaspotentialanticanceragents,Bioorg.Med.Chem.,2011,19,6518–6524.4.You-YiXia,Hai-LiangZhu*,Polyanilinenanofiber-reinforcedconctinghydrogelwithuniquepH-sensitivity,SoftMatter,2011,7,9388-9393.5.YinLuo,YaoLi,Ke-MingQiu,XiangLu,JieFu,Hai-LiangZhu*,Metronidazoleacidacylsulfonamide:AnovelclassofanticanceragentsandpotentialEGFRtyrosinekinaseinhibitors,Bioorg.Med.Chem.2011,19,6069-6076.6.Ya-PingHou,JuanSun,Zhong-HuaPang,Peng-ChengLv,Dong-DongLi,LiYan,Hong-JiaZhang,EmilyXiZheng,JingZhao,Hai-LiangZhu*,Synthesisandantitumoractivityof1,2,4-triazoleshaving1,4-benzodioxanfragmentasanovelclassofpotentmethionineaminopeptidasetypeIIinhibitors,Bioorg.Med.Chem.2011,19,5948-5954.7.Zhu-PingXiao,Tao-WuMa,Mei-LinLiao,Yu-TingFeng,Xiao-ChunPeng,Jia-LiangLi,Zhi-PingLi,YingWu,QunLuo,YangDeng,XiaoLiang,Hai-LiangZhu*,Tyrosyl-tRNAsynthetaseinhibitorsasantibacterialagents:Synthesis,moleculardockingandstructureeactivityrelationshipanalysisof3-aryl-4-arylaminofuran-2(5H)-ones,Eur.J.Med.Chem.,2011,46,4904-4914.8.JuanSun,Yu-ShunYang,WeiLi,Yan-BinZhang,Xiao-LiangWang,Jian-FengTang,Hai-LiangZhu*,Synthesis,BiologicalEvaluationandMolecularDockingStudiesof1,3,4-ThiadiazoleDerivativesContaining1,4-BenzodioxanasPotentialAntitumorAgents,Bioorg.Med.Chem.Lett.,2011,21,6116-6121.9.Hong-JiaZhang,XuanQin,KaiLiu,Di-DiZhu,Xiao-MingWang,Hai-LiangZhu*,Synthesis,antibacterialactivitiesandmoleculardockingstudiesofSchiffbasesderivedfromN-(2/4-benzaldehyde-amino)phenyl-N0-phenyl-thiourea,Bioorg.Med.Chem.2011,19,5708-5715.10.Peng-ChengLv,Dong-DongLi,Qing-ShanLi,XiangLu,Zhu-PingXiao,Hai-LiangZhu*,Synthesis,moleculardockingandevaluationofthiazolyl-pyrazolinederivativesasEGFRTKinhibitorsandpotentialanticanceragents,Bioorg.Med.Chem.Lett.2011,21,5374-5377.11.JuanSun,NingCao,Xiao-MinZhang,Yu-ShunYang,Yan-BinZhang,Xiao-MingWang,Hai-LiangZhu*,Oxadiazolederivativescontaining1,4-benzodioxanaspotentialimmunosuppressiveagentsagainstRAW264.7cells,Bioorg.Med.Chem.2011,19,4895-4902.12.YinLuo,Ke-MingQiu,XiangLu,KaiLiu,JieFu,Hai-LiangZhu*,Synthesis,biologicalevaluation,andmolecularmodelingofcinnamicacylsulfonamidederivativesasnovelantitubulinagents,Bioorg.Med.Chem.2011,19,4730-4738.13.Dong-DongLi,Peng-ChengLv,HuiZhang,Hong-JiaZhang,Ya-PingHou,KaiLiu,Yong-HaoYe,Hai-LiangZhu*,Thecombinationof4-anilinoquinazolineandcinnamicacid:Anovelmodeofbindingtotheepidermalgrowthfactorreceptortyrosinekinase,Bioorg.Med.Chem.2011,19,5012-5022.14.Zhen-WeiZhu,LeiShi,Xiao-MingRuan,YingYang,Huan-QiuLi,Suo-PingXu,Hai-LiangZhu*,SynthesisandantiproliferativeactivitiesagainstHep-G2ofsalicylanidederivatives:potentinhibitorsoftheepidermalgrowthfactorreceptor(EGFR)trrosinekinase,J.Enzym.Inhibit.Med.Chem.,2011,26(1),37-45.15.Zi-LinLi,Qing-ShanLi,Hong-JiaZhang,YangHu,Di-DiZhu,Hai-LiangZhu*,Design,synthesisandbiologicalevaluationofureaderivativesfromo-hydroxybenzylaminesandphenylisocyanateaspotentialFabHinhibitors,Bioorg.Med.Chem.2011,19,4413-4420.16.Hong-JiaZhang,Di-DiZhu,Zi-LinLi,JuanSun,Hai-LiangZhu,Synthesis,molecularmodelingandbiologicalevaluationofb-ketoacyl-acylcarrierproteinsynthaseIII(FabH)asnovelantibacterialagents,Bioorg.Med.Chem.2011,19,4513-4519.17.Xian-FengHuangandHai-LiangZhu*,ResveratrolandItsAnalogues:PromisingAnticancerAgents,Curr.Med.Chem.-Anti-Can.Agents,2011,11,479-490.18.JieFu,ShengSheng,TengWen,Zhi-MingZhang,QingWang,Qiu-XiangHu,Qing-ShanLi,Shu-QingAn,Hai-LiangZhu*,PolycyclicaromatichydrocarbonsinsurfacesedimentsoftheJialuRiver,Ecotoxicology,2011,20,940-950.19.Zhu-PingXiao,HuiOuyang,Xu-DongWang,Peng-ChengLv,Ze-JunHuang,She-RongYu,Tian-FangYi,Ye-LingYang,Hai-LiangZhu*,4-Alkoxy-3-arylfuran-2(5H)-onesasinhibitorsoftyrosyl-tRNAsynthetase:Synthesis,moleculardockingandantibacterialevaluation,Bioorg.Med.Chem.2011,19,3884-3891.20.Xin-HuaLiu,Ban-FengRuan,Jing-XinLiu,Bao-AnSong,Ling-HongJing,JunLi,YangYang,Hai-LiangZhu*andXing-BaoQi,DesignandsynthesisofN-phenylacetyl(sulfonyl)4,5-dihydropyrazolederivativesaspotentialantitumoragents,Bioorg.Med.Chem.Lett.,2011,21,2916-2920.21.Ban-FengRuan,XiangLu,Jian-FengTang,YaoWei,Xiao-LiangWang,Yan-BinZhang,Li-ShengWangandHai-LiangZhu*,Synthesis,biologicalevaluation,andmoleculardockingstudiesofresveratrolderivativespossessingchalconemoietyaspotentialantitubulinagents,Bioorg.Med.Chem.2011,19,2688-2695.22.JieFu,Yan-HuaDing,LuoLi,ShengSheng,TengWen,Lu-JiYu,WuChen,Shu-QingAn*andHai-LiangZhu*,PolycyclicaromatichydrocarbonsandecotoxicologicalcharacterizationofsedimentsfromtheHuaiheRiver,China,J.Environ.Monit.,2011,13,597-604.23.Zhu-PingXiao,Xing-BingHe,Zhij-YunPeng,tao-JuXiong,JuanPeng,Li-HuaChenandHai-LiangZhu*,Synthesis,structure,moleculardocking,andstructure–activityrelationshipanalysisofenamines:3-Aryl-4-alkylaminofuran-2(5H)-onesaspotentialantibacterials,Bioorg.Med.Chem.2011,19,1571-1579.24.Z.-P.Xiao,Z.-Y.Peng,M.-J.Peng,W.-B.Yan,Y.-Z.OuyangandHai-LiangZhu*,FlavonoidsHealthBenefitsandTheirMolecularMechanism,Mini-Rev.Med.Chem.,2011,11,169-177.25.Ban-FengRuan,Yu-PengTian,Ren-TaoHu,Hong-PingZhou,Jie-YingWu,Jia-XiangYangandHai-LiangZhu*,Synthesis,crystalstructuresandinvitroantibacterialactivityoftwonovelorganotin(IV)complexes,Inorg.Chim.Acta,2011,365,473-479.26.Ban-FengRuan,Yu-PengTian,Hong-PingZhou,JieYingWu,Ren-TaoHu,Chen-HaoZhu,Jia-XiangYangandHai-LiangZhu*,Synthesis,characterizationandinvitroantitumoractivityofthreeorganotin(IV)complexeswithcarbazoleligand,Inorg.Chim.Acta,2011,365,302-308.27.LeiShi,Zi-LinLi,YingYang,Zhen-WeiZhu,Hai-LiangZhu*,DesignofnovelN-phenylnicotinamidesasselectivecyclooxygenase-1inhibitors,Bioorg.Med.Chem.Lett.,2011,21,121-124.28.Peng-ChengLv,Tian-TianCai,YongQian,JuanSun,Hai-LiangZhu*,Synthesis,biologicalevaluationofchrysinderivativesaspotentialimmunosuppressiveagents,Eur.J.Med.Chem.,2011,46,393-398.29.Peng-ChengLv,JingXiong,JinChen,Kai-RuiWang,Wen-JunMaoandHai-LiangZhu*,Noveldepsidesaspotentialanti-inflammatoryagentswithpotentinhibitoryactivityagainstEscherichiacoli-incedinterleukin-8proction,J.Enzym.Inhibit.Med.Chem.,2010,25(4),590-595.30.Yong-MingCui,Wen-xuanYan,Ying-JieCai,WuChenandHai-LiangZhu*,Synthesis,moleculardocking,andinhibitoryactivityofaNiSchiff-basecomplexagainsturease,J.Coord.Chem.,2010,63(21),3706-3713.31.JieFu,YingYang,Xue-WeiZhang,Wen-JunMao,Zhi-MingZhang,Hai-LiangZhu*,Discoveryof1H-benzo[d][1,2,3]triazol-1-yl3,4,5-trimethoxybenzoateasapotentialantiproliferativeagentbyinhibitinghistonedeacetylase,Bioorg.Med.Chem.2010,18,8457–8462.32.YongQian,Hong-JiaZhang,Peng-ChengLv,Hai-LiangZhu*,Synthesis,molecularmodelingandbiologicalevaluationofguanidinederivativesasnovelantitubulinagents,Bioorg.Med.Chem.2010,18,8218-8225.33.Qing-ZhongZheng,Xiao-MinZhang,YingXu,KuiCheng,Qing-CaiJiao,Hai-LiangZhu*,Synthesis,biologicalevaluation,andmoleculardockingstudiesof2-chloropyridinederivativespossessing1,3,4-oxadiazolemoietyaspotentialantitumoragents,Bioorg.Med.Chem.2010,18,7836-7841.34.YingYang,LeiShi,YangZhou,Huan-QiuLi,Zhen-WeiZhu,Hai-LiangZhu*,Design,synthesisandbiologicalevaluationofquinolineamidederivativesasnovelVEGFR-2inhibitors,Bioorg.Med.Chem.Lett.2010,20,6653-6656.35.Zhu-PingXiao*,Tao-WuMa,Wei-ChangFu,Xiao-ChunPeng,Ai-HuaZhang,Hai-LiangZhu*,Thesynthesis,structureandactivityevaluationofpyrogallolandcatecholderivativesasHelicobacterpyloriureaseinhibitors,Eur.J.Med.Chem.,2010,45,5064-5070.36.Huan-QiuLi,Peng-ChengLv,LeiShiandHai-LiangZhu*,Structure-basedDiscoveryofNovelAntibacterials,Curr.Med.Chem.-Anti-InfectiveAgents,2010,9,168-179.37.Ban-FengRuan,Ten-TaoHu,Yu-PengTian*,Jie-YingWu,Hai-LiangZhu*,Synthesis,characterization,andbiologicalactivityofaCu(I)complexwith2-(9H-carbazol-9-yl)aceticacid,J.Coord.Chem.2010,63(17),2999-3005.38.Suo-PingXu,LeiShi,YuanPei,YingYang,Hai-LiangZhu*,Synthesisandantibacterialactivitiesofcopper(II)with,[(2-hydroxy-3,5-diiodo-benzylidene)-amino]-aceticacid,J.Coord.Chem.2010,63(19),3463-3470.39.Xin-HuaLiu,Hui-FengLiu,JinChen,YangYang,Bao-AnSong,Lin-ShanBai,Jing-XinLiu,Hai-LiangZhu*,Xing-BaoQi,Synthesisandmoleculardockingstudyofnovelcoumarinderivativescontaining4,5-dihydropyrazolemoietyaspotentialantitumoragents,Bioorg.Med.Chem.Lett.2010,20,5705-5708.40.WuChen,YuguangLi,YongmingCui,XianZhang,Hai-LiangZhu*,QingfuZeng*,Synthesis,moleculardockingandbiologicalevaluationofSchiffbasetransitionmetalcomplexesaspotentialureaseinhibitors,Eur.J.Med.Chem.,2010,45,4473-4478.41.Suo-PingXu,Hai-LiangZhu*,Synthesisandantimicrobialactivitiesofmetal(II)complexeswith2,4-diiodo-6-phenyliminomethyl-phenol,J.Coord.Chem.2010,63(18),3291-3300.42.LeiShi,Rui-QinFang,Zhen-WeiZhu,YingYang,KuiCheng,Wei-QingZhong,Hai-LiangZhu*,Designandsynthesisofpotentinhibitorsofb-ketoacyl-acylcarrierproteinsynthaseIII(FabH)aspotentialantibacterialagents,Eur.J.Med.Chem.,2010,45,4358-4364.43.Peng-ChengLv,JuanSun,YinLuo,YingYang,Hai-LiangZhu*,Design,synthesis,andstructure–activityrelationshipsofpyrazolederivativesaspotentialFabHinhibitors,Bioorg.Med.Chem.Lett.2010,20,4657-4660.44.YongQian,Hong-JiaZhang,HaoZhang,ChenXu,JingZhao,Hai-LiangZhu*,Synthesis,molecularmodeling,andbiologicalevaluationofcinnamicacidmetronidazoleesterderivativesasnovelanticanceragents,Bioorg.Med.Chem.2010,18,4991-4996.45.Huan-QiuLi,YinLuo,RanSong,Zi-LinLi,TaoYan,Hai-LiangZhu*,Design,Synthesis,andImmunosuppressiveActivityofNewDeoxybenzoinDerivatives,ChemMedChem,2010,5(7),1117-1122.46.YinLuo,Huan-QiuLi,YangZhou,Zi-LinLi,Hai-LiangZhu*,Metronidazole-DeoxybenzoinDerivativesasAnti-HelicobacterpyloriAgentswithPotentInhibitoryActivityagainstHPEIncedInterleukin-8,ChemMedChem,2010,5(7),1110-1116.47.YongQian,Gao-YuanMa,ALv,Hai-LiangZhu,JingZhaoandVHRawal,Squaramide-catalyzedenantioselectiveFriedel-Craftsreactionofindoleswithimines,Chem.Commun.,2010,46(17),3004-6.48.Xin-HuaLiu,Hui-FengLiu,XuShen,Bao-AnSong,PinakiS.Bhary,Hai-LiangZhu*,Jin-XingLiu,Xing-BaoQi,Synthesisandmoleculardockingstudiesofnovel2-chloro-pyridinederivativescontainingflavonemoietiesaspotentialantitumoragents,Bioorg.Med.Chem.Lett.,2010,20,4163-4167.49.Peng-ChengLv,Huan-QiuLi,JuanSun,YangZhou,Hai-LiangZhu*,Synthesisandbiologicalevaluationofpyrazolederivativescontainingthioureaskeletonasanticanceragents,Bioorg.Med.Chem.2010,18,4606-4614.50.YongQian,Gao-YuanMa,YingYang,KuiCheng,Qing-ZhongZheng,Wen-JunMao,LeiShi,JingZhao*,Hai-LiangZhu*,Synthesis,molecularmodelingandbiologicalevaluationofdithiocarbamatesasnovelantitubulinagents,Bioorg.Med.Chem.2010,18,4310-4316.51.JieFu,TengWen,QingWang,Xue-WeiZhang,Qing-FuZeng*,Shu-QingAn*andHai-LiangZhu*,DegradationofActiveBrilliantRedX-3Bbyamicrowavedischargeelectrodelesslampinthepresenceofactivatedcarbon,Environ.Technol.,2010,31(7),771-779.52.Qing-ZhongZheng,KuiCheng,Xiao-MinZhang,KaiLiu,Qing-CaiJiao*,Hai-LiangZhu*,SynthesisofsomeN-alkylsubstitutedureaderivativesasantibacterialandantifungalagents,Eur.J.Med.Chem.,2010,45,3207-3212.53.Yong-MiaoShen,Peng-ChengLv,WuChen,Peng-GangLiu,Ming-ZhuZhang,Hai-LiangZhu*,SynthesisandantiproliferativeactivityofindolizinederivativesincorporatingacyclopropylcarbonylgroupagainstHep-G2cancercellline,Eur.J.Med.Chem.,2010,45,3184-3190.54.JieFu,KuiCheng,Zhi-MingZhang,Rui-QinFang,Hai-LiangZhu*,Synthesis,structureandstructure–activityrelationshipanalysisofcaffeicacidamidesaspotentialantimicrobials,Eur.J.Med.Chem.,2010,45,2638-2643.55.KuiCheng,Qing-ZhongZheng,JinHou,YangZhou,Chang-HongLiu*,JingZhao*,Hai-LiangZhu*,Synthesis,molecularmodelingandbiologicalevaluationofPSBastargetedantibiotics,Bioorg.Med.Chem.2010,18,2447-2455.56.Huan-QiuLi,YinLuo,Peng-ChengLv,LeiShi,Chang-HongLiu*,Hai-LiangZhu*,DesignandsynthesisofnoveldeoxybenzoinderivativesasFabHinhibitorsandanti-inflammatoryagents,Bioorg.Med.Chem.Lett.2010,20,2025-2028.57.LeiShi,YingYang,Zi-LinLi,Zhen-WeiZhu,Chang-HongLiu*,Hai-LiangZhu*,Designofnovelnicotinamidesaspotentandselectivemonoamineoxidaseinhibitors,Bioorg.Med.Chem.2010,18,1659-1664.58.Peng-ChengLv,Kai-RuiWang,Qing-ShanLi,JinChen,JuanSun,Hai-LiangZhu*,Design,synthesisandbiologicalevaluationofchrysinlong-chainderivativesaspotentialanticanceragents,Bioorg.Med.Chem.2010,18,1117-1123.59.Qing-ZhongZheng,FeiZhang,KuiCheng,YingYang,YuChen,YongQian,Hong-JuanZhang,Huan-QiuLi,Chang-FangZhou,Shu-QingAn*,Qing-CaiJiao*,Hai-LiangZhu*,Synthesis,biologicalevaluationandmoleculardockingstudiesofamide-coupledbenzoicnitrogenmustardderivativesaspotentialantitumoragents,Bioorg.Med.Chem.2010,18,880-886.60.Peng-ChengLv,Chang-FangZhou,JinChen,Peng-GangLiu,Kai-RuiWang,Wen-JunMao,Huan-QiuLi,YingYang,JingXiong,Hai-LiangZhu*,Design,synthesisandbiologicalevaluationofthiazolidinonederivativesaspotentialEGFRandHER-2kinaseinhibitors.Bioorg.Med.Chem.2010,18,314-319.61.Huan-QiuLi,TaoYan,YingYang,LeiShi,Chang-FangZhou*,Hai-LiangZhu*,Synthesisandstructure–activityrelationshipsofN-benzyl-N-(X-2-hydroxybenzyl)-N0-phenylureasandthioureasasantitumoragents.Bioorg.Med.Chem.2010,18,305-313.六、部分发明专利1、朱海亮、李冬冬、王晓亮、李静然、孙建、杜茜如、方飞,4-苯胺喹唑啉类和取代肉桂酸的复合物及其制备方法与用途,申请号:201110315166.92、朱海亮、孙娟、张雁滨、杨雨顺、王晓亮、张飞,一类噻唑琳酮衍生物及其制法,申请号:201110308986.53、朱海亮、王晓亮、张雁滨、杨雨顺、汤剑锋、张飞,香草酸酰腙类衍生物及其制备和用途,申请号:201110309009.74、朱海亮、胡杨、张雁滨、王晓亮、杨雨顺,1,3,4-噁二唑类化合物的制备及其在抗癌治疗药物中的应用,申请号:201110308980.85、朱海亮、骆银、裘科明。肉桂酰磺酰胺类化合物的制备及其在抗癌治疗中的应用。申请号:201110170735.5。6、朱海亮、付杰、张雪薇、杨先辉、张莉蓉、刘常宏、张平、宋双。新型藻类隔开培养装置。申请号:2011050900142460。7、朱海亮、张志明、张雪薇、燕茹。2,5-二取代-1,3,4-噁二唑衍生物及其制法与用途。申请号:201110087058.0。8、朱海亮、付杰、杨先辉、张雪薇、张莉蓉、何祯祥。光皮树油在减肥药物开发中的应用,申请号201110063909.8。9、朱海亮、张晓敏、孙娟、刘凯、杨雨顺、燕茹、张雁滨,含1,4-苯并二噁烷的1,3,4-噁二唑衍生物的制法及其在抗癌药物中应用,申请号201110073034.X10、朱海亮、付杰、张莉蓉、张雪薇、杨先辉、何祯祥,光皮树油在降血脂药物中的应用,申请号201110063909.8。11、朱海亮、孙娟、杨雨顺、张晓敏、章虹佳、刘凯、李子琳秦旋,含1,4-苯并二噁烷的噻二唑衍生物及其制法与其抗菌活性,申请号201110063740.6。12、朱海亮、章虹佳、祝迪迪、孙娟、李子琳,塞克硝唑肉桂酸酯衍生物的合成及其在抗菌药物方面的应用,申请号201110063758.6。13、朱海亮、郑庆忠、张晓敏、董凯、焦庆才。2-氯吡啶衍生物及其制法与在制备抗肝癌药物中的应用,申请号:201010244869.2,公开号:CN101914095A。14、朱海亮、郑庆忠、刘凯、董凯、焦庆才。1,3,4-噁二唑衍生物及其制法与在制备抗肿瘤药物中的应用,申请号:201010240482.X,公开号:CN101914094A。15、朱海亮、付杰、张志明。苯并三唑衍生物及其制法与用途,申请号201010222902.1,申请日:2010.07.09,公开日:2010.12.29,公开号CN101928254A。16、朱海亮、吕鹏程、王开锐、陈进。一类含有吡唑环的硫脲类衍生物及其制法和用途,申请号:200910263121.4,公开号:CN10173515017、朱海亮、骆银、李环球。苯并三唑衍生物及其制法与用途,申请号201010222902.118、朱海亮、骆银、李环球。一种肟类化合物及其制备方法与用途,申请号200910233389.319、朱海亮、郑庆忠、程魁、焦庆才。苯甲酸氮芥衍生物及其制备方法与用途,申请号200910036290.420、朱海亮、吕鹏程、王开锐、陈进、毛文君。一类白杨素和取代水杨酸酯复合物及其制法和用途,申请号:201010111304.7,公开号:CN10176814721、朱海亮、王开锐、吕鹏程。白杨素长链衍生物及其制备方法与用途,申请号:201010111246.8,公开号:CN101774994A22、朱海亮、肖竹平、钱勇。3-芳基喹啉类化合物及其制法和用途,申请号:201010111249.1,公开号:CN10175963523、朱海亮、吕鹏程、阮班锋、孙娟、陈进。一类含有吡唑环的噻唑类衍生物及其制法和用途,申请号:200910264116.5,公开号:CN101759695,授权号ZL200910264116.5。24、朱海亮、吕鹏程、王开锐、陈进。一类含有吡唑环的硫脲类衍生物及其制法和用途,申请号:200910263221.4.25、朱海亮、李青山、李环球、严涛、骆银。一类尿素衍生物及其制法与用途,申请号:200910262954.9,公开号:CN101735113.26、朱海亮,祝祯伟,石磊,杨莹水杨酰苯胺类衍生物及其制法与用途。专利申请号200910233731.X27、朱海亮、杨莹、石磊、祝祯伟。N-喹啉酰胺类衍生物及其制法与用途,申请号:200910232198.5,公开号:CN101723894.28、朱海亮、吕鹏程。一类新型白杨素和取代水杨酸酯复合物及其制法和用途,申请号:200910184606.4.29、朱海亮、毛文君、吕鹏程。甲硝唑和取代水杨酸的复合物及其制法与用途,申请号:200910027775.7.公开号CN101560189A;授权号ZL200910027775.7.30、朱海亮、李环球、严涛。一类硫脲类衍生物及其制备方法与用途,申请号:200910031329.3.公开号CN101560175A31、朱海亮,宋忠诚,马高远,吕鹏程,石磊。一类新型N-叔丁基化噻唑烷酸类化合物及其制法和用途.申请号:200810234101.X。公开号:CN101407502。授权号:ZL200810234101.X。32、朱海亮,吕鹏程,宋忠诚。一类新型缩酚酸类化合物及其制法和用途。申请号:200810020994.8。公开号:CN101333166。33、朱海亮、石磊、宋忠诚,1,4-丁二磺酸钠的制备方法,申请号2007101918947,公开号CN101219976A,授权号ZL200710191894.7.34、朱海亮,李环球,石磊,曹平,尿素类衍生物及其制备方法与用途,申请号200710190629.7,公开号CN101161645A,授权号ZL200710190629.7.35、朱海亮,肖竹平,张丽娜,徐琛,喹啉类鸢尾黄素电子等排体及其制法和用途,申请号2006101613662,公开号CN100999492A,授权号ZL200610161366.2. 如果发现导师信息存在错误或者偏差,欢迎随时与我们联系,以便进行更新完善。(联系方式)
-
徐恒戬性别:男出生年月:1966,09职称及任职时间:副教授,2007指导层次:√硕士指导一级学科:生物学学历/学位:博士毕业院校及时间:
-
赵博生男,1962年出生,山东青州人,中共党员,博士,教授,硕士研究生导师。全国先进工作者,山东省细胞生物学会常务理事,,JournalofBiomolecularStructu
-
张秀珍性别:女出生年月:1977.07职称及任职时间:副教授,2011.1指导层次:硕士学历/学位:研究生/博士毕业院校及时间:中国科学院昆明动物所、200
-
赵凤云性别:女出生年月:1963.12职称及任职时间:教授,2010.1指导层次:√硕士指导一级学科:生物科学学历/学位:博士毕业院校及时间
-
宋关玲性别:女出生年月:1971.11职务:教师职称及任职时间:副教授,2007.01指导层次:√硕士/博士指导一级学科:生物化学与分子生物学
-
宋林霞性别:女出生年月:1972.7职称及任职时间:副教授,2007指导层次:硕士指导一级学科:生物学学历/学位:博士毕业院校及时间:河北师范大学,20
-
孔玲性别:女出生年月:1974.09职务:职称及任职时间:副教授,2005.01指导层次:√硕士指导一级学科:生物物理学学历/学位:博
-
刘文,性别:女出生年月:1966.7职称及任职时间:副教授。1999.10指导层次:硕士/博士硕士学历/学位:本科/硕士毕业院校及时间:复旦大学、1998.6