学习经历2010年3月—2011年3月，美国宾夕法尼亚大学化学系,访问学者，合作者PatrickJ.Walsh教授。2000年9月—2003年6月，兰州大学生命科学学院生物化学与分子生物学研究所，从事博士学位的学习和研究工作，获得理学博士学位，导师王锐教授。1998年9月—2000年6月，兰州大学生命科学学院生物化学与分子生物学研究所，从事硕士学位的学习和研究工作，获得理学硕士学位，导师王锐教授。1986年9月—1990年6月，兰州大学原生物系植物生理专业学习，获得理学学士学位。工作经历2012-,兰州大学，生命科学学院生物化学与分子生物学研究所，教授，博士生导师。2010-2012，兰州大学，生命科学学院生物化学与分子生物学研究所，副教授，博士生导师。2007-2010，兰州大学，生命科学学院生物化学与分子生物学研究所，副教授，硕士生导师。2005-2007，兰州大学，生命科学学院生物化学与分子生物学研究所，讲师，硕士生导师。2003-2005，兰州大学，生命科学学院生物化学与分子生物学研究所，讲师。1990-1997，甘肃省科学院，生物研究所，研究实习员。教学及指导研究生情况本科生教学，主讲《生物化学》发表论文及专著一、发表SCI论文情况PeiWang,Hong-FengLi,Jia-ZhenZhao,Zhi-HongDu,andChao-ShanDa,OrganocatalyticEnantioselectiveCross-AldolReactionofo-HydroxyarylketonesandTrifluoromethylKetones,Org.Lett.,2017,19,2634–2637.(pdf)PeiWang,YueLiu,Ya-LunZhangandChao-ShanDa,TheinexpensiveadditiveN-methylmorpholineeffectivelydecreasestheequivalentsofnucleophilesinthecatalytichighlyenantioselectivearylationofarylaldehydes,Chirality2017,DOI:10.1002/chir.22709.(pdf)PeiWang,Jia-ZhenZhao,Hong-FengLi,Xiang-MingLiang,Ya-LunZhang,Chao-ShanDa,Acid-catalyzedhighlydiastereoselectiveandeffectivesynthesisof1,3-disubstitutedtetrahydropyrano[3,4-b]indoles,TetrahedronLett.2017,58,129-133.（pdf）Wen-WenXie,YueLiu,RuiYuan,DanZhao,Tian-ZhiYu,JianZhang,Chao-ShanDa,TransitionMetal-FreeHomocouplingofUnactivatedElectron-DeficientAzaarenes,Adv.Synth.Catal.2016,358,994-1002.(pdf)LongQin,PeiWang,YixinZhang,ZhengxiangRen,XinZhang,Chao-ShanDa,DirectAsymmetricFriedel–CraftsReactionofNaphtholswithAcetalsCatalyzedbyChiralBr?nstedAcids,Synlett2016,27,571–574.(pdf)RuiYuan,DanZhao,Li-YuanZhang,XiangPan,YanYang,PeiWang,Hong-FengLi,Chao-ShanDa,Isopropylmagnesiumchloride-promotedunilateraladditionofGrignardreagentstoβ-diketones:one-potsynthesesofβ-tertiaryhydroxylketonesor3-substitutedcyclic-2-enones,Org.Biomol.Chem.2016,14,724-728.(pdf)PeiWang,Yan-EJia,Jia-ZhenZhao,DanZhao,RuiYuan,Chao-ShanDa,DesignandSynthesisofChiralBinaphthol-DerivedBisphosphoricAcidsandTheirApplicationintheCatalyticEnantioselectiveHydrogenationofQuinolines,AsianJ.Org.Chem.2015,4,430–433.（pdf）Yong-XinYang,YueLiu,LeiZhang,Yan-EJia,PeiWang,Fang-FangZhuo,Xian-TaoAn,andChao-ShanDa,ArylBromidesasInexpensiveStartingMaterialsintheCatalyticEnantioselectiveArylationofArylAldehydes:theAdditiveTMEDAEnhancestheEnantioselectivity,   J.Org.Chem.2014,79,10696-10702.(pdf)LinSun,Qi-PengGuo,XiaoLi,LeiZhang,Yu-YanLiandChao-ShanDa,C2-SymmetricHomobimetallicZincComplexesasChiralCatalystsfortheHighlyEnantioselectiveHydrophosphonylationofAldehydes,AsianJ.Org.Chem.2013,2,1031-1035.(pdf)(html)?LeiZhang,LinSun,Yu-YanLi,YueLiu,Yong-XinYang,RuiYuan,PeiWang,Chao-ShanDa,CatalyticAsymmetricArylationofEnalstoEnantioenrichedLinearTrisubstitutedAllylicSecondaryAlcoholsbyusingArylLithiumsGeneratedIn?SitufromArylBromides，ChemCatChem2013,5,3516-3519.(pdf)(html)??Zhi-XueDu,Li-YuanZhang,Xin-YuanFan,Feng-ChunWu,Chao-ShanDa,HighlyEnantioselectiveBiomimeticIntramolecularDehydration:KineticResolutionofβ-HydroxyKetonesCatalyzedbyβ-TurnTetrapeptides,TetrahedronLett.2013,54,2828-2832.(pdf)(html)Fang-FangZhuo,Wen-WenXie,Yong-XinYang,LeiZhang,PeiWang,RuiYuan,Chao-ShanDa,TMEDA-AssistedEffectiveDirectortho-ArylationofElectron-DeficientN-heteroareneswithAromaticGrignardReagents,J.Org.Chem.2013,78,3243-3249.(pdf)(html)Zhang,J.;Stanciu,C.;Wang,B.;Hussain,M.M.;Da,C.S.;Carroll,P.J.;Dreher,S.D.;Walsh,P.J.Palladium-CatalyzedAllylicSubstitutionwith(η6-Arene-CH2Z)Cr(CO)3-BasedNucleophiles.J.Am.Chem.Soc.2011,133,20552-20560.(pdf)(html)Qin,L.;Li,L.;Yi,L.;Da,C.S.;Zhou,Y.F. DirectAsymmetricN-SpecificReactionofNitrosobenzenewithAldehydesCatalyzedbyaChiralPrimaryAmine-BasedOrganocatalyst,Chirality2011,23,527-533.(pdf)(html)Fan,X.Y.;Yang,Y.X.;Zhuo,F.F.;Yu,S.L.;Li,X.;Guo,Q.P.;Du,Z.X.;Da,C.S.AlCl3andBDMAEE:APairofPotentReactiveRegulatorsofArylGrignardReagentsandHighlyCatalyticAsymmetricArylationofAldehydesChem.Eur.J.2010,16,7988-7991.(pdf)(html)ThisworkwashighlightedbySynfacts(Yamamoto,H.;Brady,P.Synfacts2010,10,1164).Liu,Y.;Da,C.S.;Yu,S.L.;Yin,X.G.;Wang,J.R.;Fan,X.Y.;Li,W.P.;Wang,R.CatalyticHighlyEnantioselectiveAlkylationofAldehydeswithDeactivatedGrignardReagentsandSynthesisofBioactiveIntermediateSecondaryArylpropanolsJ.Org.Chem.2010,75,6869-6878.(pdf)(html)Zhu,G.J.;Da,C.S.;Jia,Y.N.;Ma,X.;Yi,L.DirectAsymmetricAldolReactionCatalyzedbyC2-symmetricalChiralPrimaryAmineOrganocatalysts, Lett.Org.Chem.2010,7,15-20.Da,C.S.;Wang,J.R.;Yin,X.G.;Fan,X.Y.;Liu,Y.;Yu,S.L.,HighlyCatalyticAsymmetricAdditionofDeactivatedAlkylGrignardReagentstoAldehydes,Org.Lett.2009,11,5578-5581.(pdf)(html).ThisworkwashighlightedbySynfacts(Lautens,M.;Candito,D.A.Synfacts2010,3,323.)andOrganicChemistry:Highlights(Taber,D.F.Org.Chem.Highlights2010,July12.)Wu,F.C.;Da,C.S.;Du,Z.X.;Guo,Q.P.;Li,W.P.;Yi,L.;Jia,Y.N.;Ma,X.N-Primary-Amine-Terminalβ-TurnTetrapeptidesasOrganocatalystsforHighlyEnantioselectiveAldolReaction,J.Org.Chem.2009,74,4812-4818.(pdf)(html).Da,C.S.;Che,L.P.;Guo,Q.P.;Wu,F.C.;Ma,X.;Jia,Y.N. 2,4-DinitrophenolasAnEffectiveCocatalyst:GreatlyImprovingtheActivitiesandEnantioselectivitiesofPrimaryAmineOrganocatalystsforAsymmetricAldolReactions,J.Org.Chem.2009,74,2541-2546.(pdf)(html).Ma,X.;Da,C.S.;Yi,L.;Jia,Y.N.;Guo,Q.P.;Che,L.P.;Wu,F.C.;Wang,J.R.;Li,W.P.Highlyefficientprimaryamineorganocatalystsforthedirectasymmetricaldolreactioninbrine,Tetrahedron:Asymmetry2009,20,1419-1424.(pdf)(html)Jia,Y.N.;Wu,F.C.;Ma,X.;Zhu,G.J.;Da,C.S.Highlyefficientprolinamide-basedorganocatalystsforthedirectasymmetricaldolreactioninbrine,TetrahedronLett.2009,50,3059-3062.(pdf)(html)Yang,R.Y.;Da,C.S.;Yi,L.;Wu,F.C.;Li,H.Asymmetricconjugateadditionofunmodifiedpropionaldehydetoβ-nitrostyrenescatalyzedbyreadilyavailableproline-baseddipeptidols,Lett.Org.Chem.2009,6,44-49.Li,H.;Da,C.-S.;Xiao,Y.H.;Li,X.;Su,Y.N.DirectAsymmetricAldolReactionofArylKetoneswithArylAldehydesCatalyzedbyChiralBINOL-DerivedZincateCatalyst,J.Org.Chem.2008,73,7398-7401.(pdf)(html)Da,C.S.;Ni,M.;Han,Z.J.;Yang,F.;Wang,R.Novelnon-azacyclo1,2-aminoalcoholsderivedfromphenylalanineandhighlyenantioselectiveadditionofdiethylzinctoarylaldehydes,J.Mol.Catal.A:Chem.2006,245,1-7.(pdf)(html)Han,Z.J.;Da,C.S.;Qiu,L.;Ni,M.;Zhou,Y.F.;Wang,R.Thenaturalaminoacidderivedchiralsulfonamideligandsinthecatalyticasymmetricadditionofphenylacetylenetoaldehydes,Lett.Org.Chem.2006,3,143-148.Ni,M.;Wang,R.;Han,Z.J.;Mao,B.;Da,C.S.;Liu,L.;Chen,C.SynthesisofnewC2-symmetricalbissulfonamideligandsandapplicationintheenantioselectiveadditionofalkynylzinctoaldehydesandketones,Adv.Synth.Catal.2005,347,1659-1665.(pdf)Kang,Y.F.;Wang,R.;Liu,L.;Da,C.S.;Yan,W.J.;Xu,Z.Q.Enantioselectivealkynylationofaromaticaldehydescatalyzedbynewchiraloxazolidineligands,TetrahedronLett.2005,46,863-865.(pdf)(html)Han,Z.J.;Da,C.S.;Xu,Z.Q.;Ni,M.;Wang,R.TheasymmetricadditionofphenylacetylenetoaldehydescatalyzedbyL-leucinederivedchiralsulfonamidealcoholligands,J.Mol.Catal.A.:Chem.2005,236,32-38.(pdf)(html)Da,C.S.;Xin,Z.Q.;Xiao,Y.N.;Wang,H.S.;Su,W.;Yang,F.;Wang,R.Novelβ-AminoalcoholswithBulkySubstituentsandtheApplicationinEnantioselectiveAdditionofDiethylZinctoArylaldehydes(inChinese),Chin.J.Org.Chem.2004,24,943-945.(pdf)Zhou,Y.F.;Wang,R.;Xu,Z.Q.;Yan,W.J.;Liu,L.;Gao,Y.F.;Da,C.S.Boc-L-prolineasanewchiralligandforenantioselectivephenylacetyleneadditiontoaromaticaldehydes,Tetrahedron:Asymmetry2004,15,589-591.(pdf)(html)Xu,Z.Q.;Wang,R.;Xu,J.K.;Da,C.S.;Yan,W.J.;Chen,C.Highlyenantioselectiveadditionofphenylacetylenetoaldehydescatalyzedbyaβ-sulfonamidealcohol-titaniumcomplex,Angew.Chem.,Int.Ed.2003,42,5747-5749.(pdf)(html)Wang,H.S.;Da,C.S.;Xin,Z.Q.;Su,W.;Xiao,Y.N.;Liu,D.X.;Wang,R.EnantioselectiveconjugateadditionofdiethylzinctochalconecatalyzedbyNi(acac)2andchiralβ-aminoalcohols,Chin.J.Chem.2003,21,1105-1107.(pdf)Da,C.S.;Han,Z.J.;Ni,M.;Yang,F.;Liu,D.X.;Zhou,Y.F.;Wang,R.Aconvenientsynthesisofpiperidine-basedβ-aminoalcoholsfromL-Pheandhighlyenantioselectiveadditionofdiethylzinctoaldehydes,Tetrahedron:Asymmetry2003,14,659-665.(pdf)(html)Da,C.S.;Wei,J.;Dong,S.L.;Xin,Z.Q.;Liu,D.X.;Xu,Z.Q.;Wang,R.Highlycatalyticenantioselectiveepoxidationofenoneswithweakbasebicarbonateandhydrogenperoxide,Synth.Commun.2003,33,2787-2792.(pdf)(html)Xin,Z.Q.;Da,C.S.;Dong,S.L.;Liu,D.X.;Wei,J.;Wang,R.Anovelmethodforthesynthesisof(R)-2,2'-dihydroxy-1,1'-binaphthyl-3,3'-dicarboxylicacidbyasymmetricoxidativecouplingofachiralβ-naphtholderivativecatalyzedbyCuCl,Tetrahedron:Asymmetry2002,13,1937-1940.(pdf)(html)Liu,D.X.;Zhang,L.C.;Wang,Q.;Da,C.-S.;Xin,Z.Q.;Wang,R.;Choi,M.C.K.;Chan,A.S.C.Theapplicationofchiralaminonaphtholsintheenantioselectiveadditionofdiethylzinctoarylaldehydes,Org.Lett.2001,3,2733-2735.(pdf)(html)Yang,X.W.;Shen,J.H.;Da,C.S.;Wang,H.S.;Su,W.;Liu,D.X.;Wang,R.;Choi,M.C.K.;Chan,A.S.C.HighlyenantioselectiveadditionofdiethylzinctoaldehydescatalyzedbyanewchiralC2-symmetricTi-diolcomplex,TetrahedronLett.2001,42,6573-6575.(pdf)(html)Liu,D.X.;Wang,Q.;Zhang,L.C.;Da,C.S.;Wang,R.TrimethylsilylcyanationofAromaticAldehydesCatalyzedbyBINOL-LiSalt(inChinese),Chem.J.Chin.Univ.2001,22,601-602.(pdf)(html)Yang,X.W.;Su,W.;Liu,D.X.;Wang,H.S.;Shen,J.H.;Da,C.S.;Wang,R.;Chan,A.S.C.Preparationandapplicationofpolymer-graftedTi-BINOLcomplexesaschiralcatalystsintheenantioselectiveadditionofdiethylzinctoaldehydes,Tetrahedron2001,56,3511-3516.(pdf)(html)Yang,X.W.;Sheng,J.H.;Da,C.S.;Wang,H.S.;Su,W.;Wang,R.;Chan,A.S.C.Polymer-SupportedBINOLLigandfortheTitanium-CatalyzedDiethylzincAdditiontoAldehydes:ARemarkablePositiveInfluenceoftheSupportontheEnantioselectivityoftheCatalyst,J.Org.Chem.2000,65,295-266.(pdf)(html).Su,W.;Wang,H.S.;Da,C.S.;Wang,R.AsymmetricSynthesisofOpticallyActive1,1'-Bi-2-Naphthol(inChinese),Chem.J.Chin.Univ.2000,21,1408-1409.(pdf)(html)Wang,H.S.;Yang,X.W.;Su,W.;Liu,D.X.;Da,C.S.;Wang,R.PreparationofaPolymerSupportedBINOL-TiCatalystandItsApplicationinAsymmetricAdditionofDiethylzinctoAldehydes(inChinese),Chem.J.Chin.Univ.2000,21,1524-1525.(pdf)(html)Yang,X.W.;Shen,J.H.;Da,C.S.;Wang,R.;Choi,M.C.K.;Yang,L.;Wong,K.Chiralpyrrolidinederivativesascatalystsintheenantioselectiveadditionofdiethylzinctoaldehydes,Tetrahedron:Asymmetry1999,10,133-138.(pdf)(html)二、专利申请达朝山，谢雯雯，刘跃，一种含氮杂环芳香化合物的对称二聚体的制备方法，申请号：201510903111.8。达朝山，樊新元，卓芳芳，杨永新，不对称催化法合成光学活性二级芳基醇，申请号：CN201010188258，公开号：CN101844958，2010年5月27日，专利号：ZL201010188258.0,授权公告日：2015年11月25日。达朝山，苏亚宁，洪满贵，保英明，曹福军，一种生长抑素的合成方法，申请号：CN200910142420.2，公开号：CN101570570，2009年6月3日,专利号：ZL200910142420.2，授权公告日：2013年07月10日。三、参编书籍达朝山，王锐：高效手性配体的设计合成及其在二乙基锌对醛的不对称加成反应中的应用，《不对称有机反应》（第一版），李月明、范青华、陈新滋主编，化学工业出版社，北京，中国，2005年，第6章：pp275-291。研究方向1.合成多肽作为人工酶仿生催化的化学生物学2.手性药物的高效和绿色不对称合成3.生物活性肽的高效合成与工艺开发项目成果国家自然科学基金项目：格氏试剂的钝化及其在手性配体作用下对醛的不对称加成反应研究，国家自然科学基金，No.20672051，28万元，2007年至2009年。脱水酶的高级结构肽模拟物的设计、合成及其催化β-羰基醇脱水反应过程中的手性识别作用研究，国家自然科学基金，No.21072087,36万元，2011年至2013年。荣誉、获奖2008年甘肃省自然科学奖一等奖。完成人：王锐，许兆青，达朝山，杨晓武，张邦志。项目名称：具有重要医药用途的若干不对称催化合成方法学研究。（2008-Z1-002-R3）。2009第十六届“甘肃省普通高等学校青年教师成才奖”。社会工作甘肃省化学会第十六届理事，现任甘肃省化学会第十七届理事会理事。