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余伯阳,男,1959年出生,理学博士。中国药科大学教授、博士生导师,研究生部部长、中药学院副院长、中药复方研究室主任;国家自然科学基金生命科学部专家评议组成员,国家新药评审专家,江苏省中西医结
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一般情况寇俊萍,女,博士,中西医结合基础(药学),教授,博士生导师。国家自然科学基金中医中药学科同行评议专家,科技部国际科技合作计划评价专家,教育部科技成果与奖励评审专家,南京市科技评审专
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刘吉华,男,博士,教授,硕士研究生导师,江苏省“六大人才高峰”第五批高层次人才培养对象,江苏省“333”工程第三层次培养对象。江苏省植物生理学会常务
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中国药科大学药学院导师介绍:廖红
廖红,女,教授,博士生导师。2004年获中国药科大学药理学博士学位。联系方式:南京童家巷24号中国药科大学新药筛选中心210009Tel:025-83271043E-mail:gc
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中国药科大学药学院导师介绍:尚靖
1、一般介绍:尚靖,女,分子药理学专业,研究员,博士生导师,2002年获博士学位2、联系方式:电话:025-83271142,13813881587电子邮件:sha
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中国药科大学药学院导师介绍:于锋
一般情况姓名:于锋,性别:男学科专业:药理学和临床药学职务职称:药学院副院长、临床药学教研室主任,教授最高学历及毕业时间:博士,1998年毕业联系方式:电话:025
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中国药科大学药学院导师介绍:杨勇
杨勇,男,1976年12月生,博士、副教授。2000年获得临床医学学士学位,2005年获得药理学博士学位,主要从事基于转化医学的分子靶向抗肿瘤药物研究与开发。2009年入选教育部“新世纪优秀人才计划”,并被选为江苏省“333高层次人才培养工程”中青年科学技术带头人和江苏省“六大人才高峰”高层次人才。在国际权威学术期刊如JBC、CDD、Carcinogenesis、MolecularCancerTherapy等累计发表SCI论文30余篇,累积影响因子超过100分,研究成果得到国际学术界的高度认可,被Cancerresearch,Blood等多篇国际著名杂志引用。一篇SCI论文入选科技部中国科学技术信息研究所评出的“2008年中国百篇最具影响国际学术论文”。2011年作为项目负责人承担国家自然科学基金重大研究计划1项,国家自然科学基金面上项目2项;承担科技部“十二五重大新药创制专项”1项;承担江苏省自然科学基金2项。2005年获得“江苏省科技进步一等奖”和“中华医学三等奖”,2007年荣获“江苏省科技进步二等奖”。兼任国家自然科学基金评审专家、研究生教材《肿瘤药理学》副主编、全国高等医药院校药学类统编教材编委和Cancerresearch等多个国际学术期刊的特约审稿人。近年来发表的论文:1.ZhangWB,WangZ,SuF,JinYH,LiuHY,WangQJ,YangY*.ActivationofAMP-activatedproteinkinasebytemozolomidecontributestoapoptosisinglioblastomacellsviap53activationandmTORC1inhibition.JBiolChem.2010,285,52:40461–40471.(Correspondingauthor)2.Qing-yiZhu,ZhuoWang,ChaoJi,Yan-liYang,Yong-huaJin,Qiu-juanWang,Zhi-gangBi,Gang,Hu,YongYang*.C6-Ceramidesynergisticallypotentiatestheanti-tumoreffectsofhistonedeacetylaseinhibitorsviaAKTde-phosphorylationandα-tubulinhyper-acetylationbothinvitroandinvivo.CellDeath&Disease.(2011)2,e117;doi:10.1038/cddis.2010.96.(Correspondingauthor)3.YongYang,Lin-boZhang,LeiQiang,QingZhao,Yan-junMa,Zhi-yuLi,Qi-DongYou,Qing-LongGuo.Wogoninincedcalreticulin/AnnexinA1exposuredictatestheimmunogenicityofcancercellsinaPERK/AKTdependentmanner.PLoSONE.2011,revised.4.ChenFei-Hong;ZhangLin-Bo;QiangLei;YangZhen;WuTian;ZouMei-Juan;TaoLei;YouQi-Dong;LiZhi-Yu;YangYong*;GuoQing-Long.Reactiveoxygenspecies-mitochondriapathwayinvolvedinLY-202-incedapoptosisinhumanhepatocellularcarcinomaHepG(2)cells.Cancerletters.2010;296(1):96-105.(Correspondingauthor)5.LeiQiang,YongYang,Qi-DongYou,Yan-JunMa,etal.Inhibitionofglioblastomagrowthandangiogenesisbygambogicacid:aninvitroandinvivostudy.BiochemicalPharmacology.2008,75(5):1083-92.(Co-firstauthor)6.QiangL,YangY,YouQD,MaYJ,etal.Isolationandcharacterizationofcancerstemlikecellsinhumanglioblastomacelllines.Cancerletters.2009,279(1):13-21.(Co-firstauthor)7.JunY,GuoQL,YouQD,ZhaoL,GuHY,YangY,ZhangHW,TanZ,WangX.GambogicacidincedG2/MphasecellcyclearrestviadisturbingCDK7mediatedphosphorylationofCDC2/P34inhumangastriccarcinomaBGC-823cells.Carcinogenesis.2007,28(3)632-8.8.YongYang,LanYang,Qi-DongYou,Fei-FeiNie,Hong-YanGu,LiZhao,Xiao-TangWang,Qing-LongGuo.Differentialapoptoticinctionofgambogicacid,anovelanticancernaturalproct,onhepatomacellsandnormalhepatocytes.CancerLetters.2007,256:259-26.9.YongYang,YangHu,Hong-YanGu,NaLu,etal.OroxylinAincesG2/Mphasecell-cyclearrestviainhibitingCdk7-mediatedexpressionofCdc2/p34inhumangastriccarcinomaBGC-823cells.JournalofPharmacyandPharmacology.2008,60(11):1459-63.10.NaLu,YongYang,Qi-DongYou,YunLing,YingGao,Hong-YanGu,LiZhao,Xiao-TangWang,Qing-LongGuo.GambogicAcidInhibitsangiogenesisthroughsuppressingvascularendothelialgrowthfactor-incedtyrosinephosphorylationofKDR/Flk-1.CancerLetters.2007.258(1):80-9.(Co-firstauthor)11.QingZhao,YongYang,JunYu,Qi-DongYou,ShiZeng,Hong-YanGu,NaLu,QiQi,WeiLiu,Xiao-TangWang,Qing-LongGuo.PosttranscriptionalRegulationoftheTelomerasehTERTbyGambogicAcidinHumanGastricCarcinoma823Cells.Cancerletters.2008,262(2):223-31.(Co-firstauthor)12.YunLing,YongYang,NaLu,Qi-dongYou,SenWang,YingGao,YanChen,Qing-LongGuo.Endostar,anovelrecombinanthumanendostatin,exertsantiangiogeniceffectviablockingVEGF-incedtyrosinephosphorylationofKDR/Flk-1ofendothelialcells.BiochemicalandBiophysicalResearchCommunications.2007.361:79-84.(Correspondingauthor)13.LuN,LingY,GaoY,ChenY,MuR,QiQ,LiuW,ZhangH,GuH,WangS,YangY,GuoQ..Endostarsuppressesinvasionthroughdown-regulatingtheexpressionofmatrixmetalloproteinase-2/9inMDA-MB-435humanbreastcancercellsExperimentalBiologyandMedicine.2008,233(8):1013-20..(Correspondingauthor)14.Hai-WeiZhang,YongYang,KunZhang,LeiQiang,LiYang,LanYang,YangHu,Xiao-TangWang,Qi-DongYou,Qing-LongGuo.WogoninIncedDifferentiationandG1PhaseArrestofHumanU-937LeukemiaCellsviaPKCδPhosphorylation.EuropeanJournalofPharmacology.2008,591(1-3):7-12. (Co-firstauthor)15.GuH,WangX,RaoS,WangJ,ZhaoJ,RenFL,MuR,YangY,QiQ,LiuW,LuN,LingH,YouQ,GuoQ.Gambogicacidmediatesapoptosisasap53incerthroughdown-regulationofmdm2inwild-typep53-expressingcancercells.MolCancerTher.2008,7(10):3298-305.16.HaoLi,Qiu-JuanWang,Dan-NiZhuandYongYang.ReiniosideC,aTriterpeneSaponinofPolygalaaureocaudaDunn,exertsHypolipidemicEffectonHyperlipidemicMice.PhytotherRes.2008;22(2):159-64.(Correspondingauthor)17.Zhang,Kun;You,Qidong;Yang,Yong;Zhang,Haiwei;Yang,Li;Gu,Hongyan;Qi,Qi;Tan,Zi;Wang,Xiaotang;Guo,Qinglong.WogoninincesthegranulocyticdifferentiationofhumanNB4promyelocyticleukemiacellsandup-regulatesphospholipidscramblase1geneexpression.CancerScience.2008,99(4):689-95.18.Qi,Qi;Gu,Hongyan;You,Qidong;Yang,Yong;etal.Involvementofmatrixmetalloproteinase2and9ingambogicacidincedsuppressionofMDA-MB-435humanbreastcarcinomacelllung metastasis.JournalofMolecularandMedicine.2008,86(12):1367-77.19.QiQ,LuN,WangXT,GuHY,YangY,LiuW,LiC,YouQD,GuoQL.Anti-invasiveeffectofgambogicacidinMDA-MB-231humanbreastcarcinomacells.BiochemCellBiol.2008,86(5):386-95.20.LuN,GaoY,LingY,ChenY,YangY,GuHY,QiQ,LiuW,WangXT,YouQD,GuoQL.WogoninsuppressestumorgrowthinvivoandVEGF-incedangiogenesisthroughinhibitingtyrosinephosphorylationofVEGFR2.LifeSciences.200823;82(17-18):956-63.21.ChenJ,GuHY,LuN,YangY,LiuW,QiQ,RongJJ,WangXT,YouQD,GuoQL.Microtubuledepolymerizationandphosphorylationofc-JunN-terminalkinase-1andp38wereinvolvedingambogicacidincedcellcyclearrestandapoptosisinhumanbreastcarcinomaMCF-7cells.LifeSciences.2008;83(3-4):103-9.22.GuH,YouQ,LiuW,YangY,ZhaoL,QiQ,ZhaoJ,WangJ,LuN,LingH,GuoQ,WangX.GambogicacidincedtumorcellapoptosisbyTlymphocyteactivationinH(22)transplantedmice.IntImmunopharmacol.2008,8(11):1493-502.23.ZhaoJ,QiQ,YangY,GuHY,LuN,LiuW,WangW,QiangL,ZhangLB,YouQD,GuoQL.Inhibitionofalpha(4)integrinmediatedadhesionwasinvolvedintherectionofB16-F10melanomacellslungcolonizationinC57BL/6micetreatedwithGambogicacid.EurJPharmacol.2008,589(1-3):127-31.24.LuN,LingY,GaoY,ChenY,MuR,QiQ,LiuW,ZhangH,GuH,WangS,YangY,GuoQ..Endostarsuppressesinvasionthroughdown-regulatingtheexpressionofmatrixmetalloproteinase-2/9inMDA-MB-435humanbreastcancercellsExperimentalBiologyandMedicine.2008,revised.(Correspondingauthor)25.JunY,GuoQL,YouQD,ZhaoL,GuHY,YangY,ZhangHW,TanZ,WangX.GambogicacidincedG2/MphasecellcyclearrestviadisturbingCDK7mediatedphosphorylationofCDC2/P34inhumangastriccarcinomaBGC-823cells.Carcinogenesis.2007,28(3)632-8.26.QinglongGuo,LiZhao,YongYang,HongyanGu,GuoliangSong,NaLu,JianXin,QidongYou.Anti-hepatitisBvirusactivityofwogonininvitroandinvivo.AntiviralResearch.2007,74(1)16-24.27.YangHu,YongYang,Qi-DongYou,WeiLiu,Hong-YanGu,LiZhao,KunZhang,WeiWang,Xiao-TangWang,Qing-LongGuo.OroxylinAincedapoptosisofhumanhepatocellularcarcinomacelllineHepG2wasinvolvedinitsantitumoractivity.BiochemicalandBiophysicalResearchCommunications351(2006)521–527.(Co-firstauthor)28.WangW,GuoQL,YouQD,ZhangK,YangY,YuJ,LiuW,ZhaoL,GuHY,HuY,TanZ,WangXT.TheAnticancerActivitiesofWogonininMurineSarcomaS180bothinVitroandinVivo.BiolPharmBull.2006;29(6):1132-7.29.WangW,GuoQ,YouQ,ZhangK,YangY,YuJ,LiuW,ZhaoL,GuH,HuY,TanZ,WangX.Involvementofbax/bcl-2inwogonin-incedapoptosisofhumanhepatomacelllineSMMC-7721.AnticancerDrugs.200617(7):797-805.30.YongYang,XingLiu,YanLong,FangWang,Jian-HuaDing,Su-YiLiu,Ye-HongSun,Hong-HongYao,HaiWang,JieWu,GangHu.ActivationofmitochondrialATP-sensitivepotassiumchannelsimprovesrotenone-relatedmotorandneurochemicalalterationsinrats.TheInternationalJournalofNeuropsycopharmacology,2006;9(1):51-61.31.HuaCHEN,YongYANG,Hong-hongYAO,Xing-chunTANG,Jian-huaDING,HaiWANG,GangHU.Protectiveeffectsofiptakalim,anovelATP-sensitivepotassiumchannelopener,onglobalcerebralischemia-evokedinsultingerbil.ActaPharmacolSin2006,27(6):665-72.(Co-firstauthor)32.LiuX,WuJY,ZhouF,SunXL,YaoHH,YangY,DingJH,HuG.Theregulationofrotenone-incedinflammatoryfactorproctionbyATP-sensitivepotassiumchannelexpressedinBV-2cells.NeuroscienceLetters,2006;394(2):131-5.33.YongYang,XingLiu,YanLong,FangWang,Jian-HuaDing,Su-YiLiu,Ye-HongSun,Hong-HongYao,HaiWang,JieWu,GangHu.Systemicadministrationofiptakalim,anovelATP-sensitivepotassiumchannelopener,preventsrotenone-incedmotorandneurochemicalalterationsinrats.JournalofNeuroscienceResearch,2005;80(3):442-449.34.YangY,LiuX,DingJH,LongY,WangF,YaoHH,HuG.Effectsofiptakalimonrotenone-incedcytotoxicityanddopaminereleasefromPC12cells.NeuroscienceLetters,2004;366(1),53-57.35.SenWang,Li-fangHu,YongYang,Jian-huaDing,GangHu.StudiesofATP-sensitivepotassiumchannelson6-hydroxydopamineandhaloperidolratmodelsofParkinson’sdisease:ImplicationsfortreatingParkinson’sdisease?Neuropharmacology,2005;48(7):984-992.*如果发现导师信息存在错误或者偏差,欢迎随时与我们联系,以便进行更新完善。联系方式>>
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中国药科大学药学院导师介绍:张评浒
张评浒,男,1976年8月生,湖南新化人,博士,副研究员,硕士生导师,江苏省新药筛选中心&国家药物筛选实验室副主任。2006年毕业于扬州大学,获博士学位,2006年进入中国药科大学新药筛
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中国药科大学药学院导师介绍:张锋
基本信息姓名:张锋,性别:男学科专业:制药工程和生物化工最高学历及毕业时间:博士,2006年联系方式:电话:025-83271479(O)Email:abrem@163